RSC Anderlecht II host Lokeren-Temse in the Challenger Pro League, Belgium's second division, at Lotto Park in Anderlecht. This is the season opener for both clubs, who start on zero points. Every early result is crucial for establishing momentum in the league campaign.

For those travelling to Lotto Park, several metro stations are a short walk from the stadium, including Cours Saint-Guidon - Sint-Guidocorso, Saint-Guidon - Sint-Guido, and Avenue Gounod - Gounodlaan. Bus users can access the ground via nearby stops such as De Linde and Hôpital Joseph Bracops - Joseph Bracops-ziekenhuis.